Retinoid 160 has been PROVEN in Gold Standard Clinical Trials to work for up to ONE HUNDRED AND SIXTY HOURS after each application. But that is just the start the other 11 All Natural Ingredients found in every bottle of Retinoid 160 will give you youthful looking eyes FAST. Time Release Retinol reduces the appearance of wrinkles without irritation. Supports your own stem cells' ability to generate more new skin cells for a fresher, more youthful appearance Contains extracts from 11 plants to moisturize and protect your skin Stem Cell Eye Repair 0.5 fl. oz.